Furosemide (Furosemide) 40 mg 100 tabs Apotex Generic
Information about the drug
Furosemide is a loop diuretic, that causes fast onset, strong and short-term diuresis. It has natriuretic and chloruretic effects, increases the excretion of K +, Ca2 +, Mg2 +. The antihypertensive effectiveness of furosemide is explained by increased sodium excretion, reduced blood volume and a decreased response of vascular smooth muscles to stimulation with vasoconstrictors or vasoconstrictors. Furosemide increases the level of prostaglandins and kinins, which improves the hemodynamics of the kidneys and enhances the natriuretic effect. The drug retains uric acid in the body. A decrease in blood pressure is associated with sodium urease and a decrease in the sensitivity of the vascular wall to catecholamines.
The original task of the drug was helping to patients with hypertension lowing the blood pressure. Also, it’s useful to remove toxins with the urine from the organism and in other cases when the necessity of increased diuresis is emerged. Due to the potent natriuretic activity, furosemides are often used for dehydration therapy for cerebral and pulmonary edema, as well as for forced diuresis in case of poisoning and intoxication. The drug reduces blood pressure, so it is used for hypertension in combination with antihypertensive drugs.
Athletes involved in bodybuilding, take furosemide shortly before the competition to remove “excess” subcutaneous water and in order to look elastic, lean on the stage at the time of the competition. It’s applied in many cases, mainly before the weighing, to get the most profitable weight category.
After taking this drug, depending on the amount of excess water present in the body, more or less frequent urge to urinate is manifested. In this case, a significant loss of body weight can occur in the shortest possible time. On this basis, furosemide is taken by athletes to stabilize body weight. Athletes prefer, as a rule, the form of release of the drug for oral use. Athletes sometimes use an injectable or intravenous version on the morning of the competition, as these routes of administration are instantaneous and good when the athlete worries because of fluid left under the skin. However, this use of furosemide may have the opposite effect. It may happen that one or another athlete, a professional or an amateur who has achieved the best success, right before the start of the competition will be forced to apply all kinds of countermeasures, which are intravenous administration of glucose in order to increase blood volume and smooth out the loss of potassium; many athletes take potassium chloride tablets.
One of the main indications for the use of diuretics is various intoxication of the body. As for endogenous intoxication, the athlete is more susceptible to them than the non-athlete. This is due to catabolism processes intensified under the influence of high physical exertion, as a result of which various toxic catabolism products are accumulated in the athlete’s body – ketone bodies, ammonia, urea, uric acid, etc. Therefore, the use of diuretics could contribute to the detoxification of the athlete’s body.
Apo Firosemide 40 mg tablet is used in sports to get rid of water layer under the skin. Skilled athletes know that during the preparations to the performance necessary to break this water layer to visually make muscles more volume. But sometimes, when the fat’s level is very low, muscles can’t be traced as well. It’s because of water that becomes the interlayer between the muscles and skin. Such situation can downgrade the visual effect during the performance. But thanks to this drug, the problem can be done, carefully applying diuretic medicines.
This medicine starts the act in 45-60 minutes after the using. The validity is near 3-3.5 hours. It can be applying in small doses in a week before the performance, and bigger doses in several days before it.
The dosage should be chosen individually, firstly the effect must be tested on your body. Athletes who specialize in bodybuilding, use furosemide diuretic usually as follows: take a half or a whole 40 milligram tablet and expect the effect. Some athletes repeat this procedure after a few hours, 1-2 times more. Such schedule should be repeated 2-3 times to gain the result you need. It should be remembered that furosemide is the most powerful diuretic and one of the most dangerous drugs in the medical arsenal of bodybuilders.
Apo Furosemide 40 mg Side effects
Patients who are prescribed furosemide should be warned about the possible development of symptoms associated with excessive loss of fluid and / or electrolytes. There is a likelihood of developing orthostatic arterial hypotension. In this case, a slow change in body position is able to some extent to prevent a decrease in blood pressure during the transition from horizontal to vertical position. The addition of potassium preparations during furosemide therapy and / or adherence to a certain dietary regimen (eating potassium-rich foods) is necessary to prevent the development of hypokalemia.
Hypokalemia may manifest as the following symptoms:
- Muscle spasms;
- Weakness in the legs.
To avoid serious consequences the product should be applied in small doses and during the short time period. In patients receiving high doses of furosemide, in order to avoid the development of hyponatremia and metabolic alkalosis, it is inappropriate to limit the intake of table salt. For the prevention of hypokalemia, the simultaneous administration of K + and potassium-sparing diuretics (primarily spironolactone) is recommended, as well as a diet rich in K +.
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This drug is a medical product and requires following recommendations of its usage and storage. It should be stored in the cool dark place, avoiding direct sunlight. It’s also necessary to keep this drug out of children`s reach!
You MUST consult with your attending physician before you start using this drug. We also ask you to take into account that this drug may cause some side effects. Some of them can be life-threatening. If you notice any disturbing symptoms you should to contact with your physician. In some cases, it is necessary to stop taking the drug for a while. Also, you must inform your doctor if you taking APO-FUROSEMIDE with other medicines. So physician can prescribe proper treatment and help you to avoid any unpleasant adverse effects.