Accutane (Isotretinoin) 40 mg 30 caps Roche

Information about the drug

Accutane, or isotretinoin, is one of the most powerful and effective treatments for severe acne. This is a retinoid drug, and it is associated with vitamin A and is also found in small amounts in the body. Its isomer, tretinoin, is also a cure for acne.

Isotretinoin acts on the differentiation of keratinocytes, normalizing regeneration processes in which retinoids (derivatives of vitamin A) play a key role. Isotretinoin is able to suppress the production of sebaceous glands and reduce their number. The way of action of this product is in its property to influence on the production of fat in the pores of the skin. By reducing the amount of body fat, Accutane prevents clogging of the skin pores and prevents inflammation. Accutane also promotes faster skin regeneration, thereby saving patient from acne and its consequences. Due to this property, it has found the greatest application in dermatology in the treatment of acne. This drug is effective even in cases where antibiotics are powerless.

Acne is a common disease during the puberty. But Accutane is a very powerful drug and should be used in more complex cases of acne. It is used to treat the so-called cystic form of acne. This is one of the most complex forms of this disease and is practically not treatable. Acne pops up on the skin in the form of hard painful cysts, which are usually larger than ordinary acne. If untreated, this form can lead to scarring, as well as potential psychological problems associated with stress and self-esteem.

Acne mainly appears on areas of the skin where there are many sebaceous glands: first of all, this is the face, chest and back. As a rule, acne is inflammatory in nature; however, inflammation may be absent, depending on the form. Most often, acne occurs in adolescence, but can also be present in adults.

Acne also is a fairly common side effect from taking Androgenic Anabolic Steroids (AAS). It appears as an androgenic side effects of steroid drugs. Acne is not only an external disorder, it also has influence on the athlete’s health and may leave scars for many years. So there is an urgent need to get rid of this disorder in the early stages.

Applying

The therapeutic efficacy of Accutane pills and its side effects are dose-dependent and vary in different patients. This dictates the need for individual dose selection during treatment.

Before you start taking the drug, tell your doctor your medical history. You should tell your doctor about any diseases of a physiological or psychological nature, taking medications and supplements, including vitamins. It is also necessary to take a blood test every month to monitor changes and monitor cholesterol levels (in particular, triglycerides). Regular laboratory tests are necessary to prevent damage to the liver and kidneys while taking Accutane.

On average, for treating acne, the dose is 80 mg per day, but the corrects dosage should be calculated by dermatologist, depending on body weight and the stage of disease. It is necessary to take the drug in the morning and in the evening (one tablet), during the food intake for better absorption of active components. The duration of the course is rather individual, but the minimal effective course is 30 days. Complete remission of acne is often achieved in 16-24 weeks of treatment. In patients who tolerate the recommended dose very poorly, treatment can be continued in a lower dose, but spend it longer.

Accutane Side effects:

Most side effects of buying Accutane are dose dependent. As a rule, when prescribing recommended doses, the ratio of benefit and risk, is acceptable to the patient. Usually, side effects are reversible after dose adjustment or drug withdrawal, but some may persist after treatment is discontinued.  Main disorders that can occur are associated with the skin and the gastrointestinal tract.

With strict adherence of the recommendations, the drug will help you to get rid of acne, but in the case of wrong using you may feel unwanted side effects as:

• From the side of the central nervous system and the mental sphere: impaired behavior, depression, headache, increased intracranial pressure,
• From the digestive system: nausea, diarrhea, inflammatory bowel disease (colitis, ileitis),
• Dermatological reactions: rash, itching, sweating, persistent thinning of hair, reversible hair loss, hyperpigmentation, photosensitivity, photoallergy, mild skin injury. At the beginning of treatment, exacerbation of acne may occur, lasting several weeks.
• Effects due to hypervitaminosis A: dry skin and mucous membranes, including lips (cheilitis), nasal cavity (bleeding), larynxopharynx (hoarseness of the voice), eyes (conjunctivitis, intolerance to contact lenses).
• Laboratory indicators: hypertriglyceridemia, hypercholesterolemia, a decrease in the level of high density lipoproteins, rarely hyperglycemia. In some patients, especially those involved in intense physical activity, individual cases of increased activity of CPK in serum are described.

The drug is strictly contraindicated in established and planned pregnancy. Women should be tested for pregnancy before receiving a prescription for this drug, and properly instructed on the consequences for the fetus in the event of an unplanned pregnancy while taking the drug and within three months after its completion.

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Warning!

This drug is a medical product and requires following recommendations of its usage and storage. It should be stored in the cool dark place, avoiding direct sunlight. It’s also necessary to keep this drug out of children`s reach!

You MUST consult with your attending physician before you start using this drug. We also ask you to take into account that this drug may cause some side effects. Some of them can be life-threatening. If you notice any disturbing symptoms you should to contact with your physician. In some cases, it is necessary to stop taking the drug for a while. Also, you must inform your doctor if you taking ACCUTANE with other medicines. So physician can prescribe proper treatment and help you to avoid any unpleasant adverse effects.