Letrozole and Tamoxifen for the male: how to take it in bodybuilding, and other points

Letrozole and Tamoxifen for the male: how to take it in bodybuilding, and other points

What is better? Tamoxifen or Letrozole?

With prolonged use of various anabolic steroids, an increase in muscle mass and strength occurs. But there is a likelihood of the so-called "side effects". One of them is feminization, with an increase in mammary glands (gynecomastia), an increase in adipose tissue with the effect of smoothing the relief of muscles, poor excretion of fluid from the body and problems in the male part.

For the preventive purposes of such not-so-good side effects and their suppression, doctors give recommendations to use antiestrogens. This drugs can block the effects of female sex hormones estrogen. One of the common antiestrogens in use are letrozole and tamoxifen, bodybuilders use them, but strictly following all instructions for use.

What is better? Tamoxifen or Letrozole?

Tamoxifen: instructions for use in bodybuilding

Tamoxifen (nolvadex) is a drug against tumors that activates in the fight against selected hormone-dependent tumors, breast cancer, for example. But we want to know how tamoxifen works during physical exertion, where the result should be completely different, and the application is different from usual.

Taking steroids raises the hormonal level in men, but the body is looking for an opportunity to balance hormones and begins the process of changing testosterone to estrogen - female sex hormones. The level of estrogen increases accordingly.

The main substance that acts in the drug tamoxifen blocks estrogen receptors. Those receptors that are interconnected, cease to give an answer to an increased level of estrogen, which from a physiological point of view in the body leads to a restoration of the balance of hormones. In addition, due to the complex interaction of biologically active substances in the body, taking the drug indirectly increases the level of male sex hormone.

It turns out that the use of tamoxifen to increase male testosterone levels is justified and shows excellent achievements.

Tamoxifen Characteristics


  • Effectively prevents an increase in the level of mammary glands in men.
  • It reduces the level of adipose tissue, so it can very often be used for drying.
  • Tamoxifen is used in rehabilitation after taking AAS (a course of androgenic and anabolic steroids).
  • It gives good results in the treatment of feminizing "side effects".
  • At a cost of inexpensive preparations of antiestrogens.Disadvantages:
  • Increased toxicity of the drug is possible, but it happens when taking an excessive dose of the drug.
  • The ban on the use for therapy, after a course of taking AAS drugs, where trenbolone or nandrolone was taken.

Tamoxifen in bodybuilding: how to take

Tamoxifen Side effects:

  • Decreased appetite.
  • Nausea, indigestion.
  • Decreased potency and libido.
  • Visual impairment.
  • Increased oily skin with acne.
  • Hair loss.
  • Increased bleeding.

Often, the “side effect" clearly begins to be visible with prolonged use of the drug, as well as improper administration, for example, changing the dosage. It is worth knowing that the drug tamoxifen can affect the liver, therefore, with its unstable functioning, the drug should not be used, otherwise - keep the level of hepatic transaminases under control. Another drug can affect the decrease in platelet count in the blood, experts recommend monitoring all indicators, passing tests, in expanded form with a coagulogram.

Tamoxifen in bodybuilding: how to take

Now we will separately tell you how tamoxifen is taken in sports, we argue why.

The admission regimen for athletes is very different from the one that is prescribed in the annotations for the drug in the treatment of oncology. The normal dosage of taking the drug tamoxifen for the male is 0.01 g per day, but with a special purpose it (dose) can be raised to 0.03 g.

Taking antiestrogens is just a prophylaxis, and does not have therapeutic purposes. In this regard, there is no need to wait for gynecomastia or the end of taking AAS when the level of female hormones is significantly exceeded. According to the recommendations of specialists, the start of tamoxifen use should be after a weekly intake of the AAS course, and the end should be on the 15-20th day after the completion of the ACC course.

Athletes with experience use the drug tamoxifen after completing a course of antiestrogens from the group of aromatase inhibitors: the effectiveness in bodybuilding, after taking this way, is quite high, many positive reviews speak for it. In this combination, aromatase blockers begin to take from the 8th day of the course and thereby inhibit the conversion of testosterone to estrogens. At the final stage (last 7 days from the course), the aromatase inhibitor is changed to tamoxifen, it must be used 21 days after the course of therapy.

In a good version, the intake of tamoxifen in bodybuilding should be with the control of estrogen levels. In the case when it remains normal, apply the usual dosage (0.01 g). When the amount of estrogen increases, there is a need to increase the dose until the indicator becomes controlled and normal.

Tamoxifen Side effects:

Tamoxifen analogues

The same drug as tamoxifen in bodybuilding, similar in effect and effectiveness, is clomid (clostilbegid). Its action also leads to the binding of estrogen receptors, but this effect is a pronounced selectivity. The effectiveness of clomid is directed generally to the pituitary receptors, while tamoxifen stops receptors located in the pituitary gland and in other tissues of the human body.

Therefore, in male athletes, the effectiveness of tamoxifen is more pronounced: in clinical trials it is proved that the level of testosterone when taking tamoxifen increases much faster, and this is a consequence of reducing the dose of the drug more quickly, while the result of the work does not go away. The only positive thing about clomid, as a related analogue of tamoxifen in bodybuilding. Is the possibility of combination with substances such as trenbolone or nandrolone.

Letrozole: instructions for use in bodybuilding

The effect of a drug such as letrozole is directly related to the blocking of aromatase. This is a special enzyme that changes testosterone to estrogen. The drug exists for the treatment of estrogen-dependent tumors in women, and in sports among bodybuilders. The drug has revealed new functions: letrozole for athletes is used if there is a possibility of bad consequences of “side effects” of steroids - feminization.

Characteristics of Letrozole

Letrozole benefits:

  • Prevents gynecomastia.
  • Increases the level of biologically active substances with anabolic effects.
  • Effective for drying due to hormonal regulation of the thickness of subcutaneous fat.
  • Normalizes blood pressure.
  • Normalizes sexual function.
  • Used to eliminate the phenomena of the already arisen feminization.
  • Long half-life: can be taken 1 time in 2-3 days.
  • Acceptable price.
  • Low toxicity.

The drug has, in comparison with other analogues, minimal toxicity. But doctors advise and even force, before taking an examination in a medical organization.

Letrozole: instructions for use in bodybuilding


  • Not suitable for all steroids: lack of effect when used with boldenone and halotestin.
  • A strong decrease in estrogen is possible, and as a result, the occurrence of "side effects".

Side effects:

  • Slowing muscle growth.
  • Decreased potency.
  • Osteoporosis.
  • Increased risk of atherosclerosis.
  • Pain in bones and joints.
  • Weakness, fatigue.
  • Digestive disorders.
  • Hair loss.
  • Mental disorders: depression, anxiety, sleep disturbance, irritability, memory impairment.

Letrozole in bodybuilding: how to take

The intake of letrozole in bodybuilding and in general, it is necessary to start applying earlier before the amount of estrogen increases and the upper threshold is crossed. Moreover, this will be accompanied by swelling, impaired sexual function in men, the nipples and the area around them will expand. By the time when this, unfortunately, has already happened, treatment should not be postponed, but rather, immediately begin. The symptomatology will need to be removed, taking in a dosage every day one tablet (0.0025 g).

In a good version, letrozole should also be used for prophylaxis: to increase testosterone levels and maintain its performance. The drug is prescribed from 7-10 days of the AAS cycle in a dosage of only 1/5 tablet (0.0005 g) every other day. Such use of the drug reduces the possibility of side effects and increases the effectiveness in training athletes. When the ACC course is completed, the drug letrozole continues to be taken from 14 to 21 days. The dosage of the drug is chosen for a specific person, based on indicators or, in extreme cases, on a person’s own feelings and on the basis of his well-being.

Knowing how to use the drug letrozole, you can achieve very high results and indicators in bodybuilding. But at the same time your health level will also be maintained.